Better control of symptoms from GERD

A studio still in progress, from pre-released results

The degree of satisfaction of patients with gastroesophageal reflux disease (GERD, gastroesophageal reflux disease) would be significantly greater after surgery for via laparoscopic than during Proton pump inhibitors (PPIS).
Dr. Michael Anvari and coll.(McMaster University in Hamilton, Ontario, Canada) have randomized 104 patients with GERD (average age of 42 years) from Nissen fundoplication second Nissen for via laparoscopic or optimal treatment with IPP.Researchers at Digestive Disease Week 2006 reported obtained much better in the first group patients.
The criteria for recruitment to the study predicted the presence of GERD for at least 2 years, treatment with IPP for at least a year with a satisfactory control of symptoms (defined by a score 4% off-therapy.
Prior to randomisation patients had suspended the recruitment of all drugs.The initial score to the global Rating scales (GRS) was approximately 82, GERD score around 30 and the percentage of reflux in 24 hours around 10% for all patients who had suspended the therapy.
During the follow-up you've missed 6 patients. One year, patients with IPP had an average score of 73,3 to GRS score, a GERD score of 12,82 and a gastric reflux of 5,44%.The corresponding values in patients were 8.46 was 90.2, and 1.50%.
Dr. Anvari acknowledged that the data reported by patients are a subjective information, but said "doubting that a placebo effect may last several years".He also claimed that the surgical procedure has a little morbidity, and needs a "learning curve". In its Centre, however, "the success of the methodology is becoming less operator-dependent".
Fourteen of the patients they recur, easily controlled by resuming the pharmacological treatment with IPP. "Are provisional data, the study is still ongoing "has finally remembered at Dr.Anvari."and it is too early to draw conclusions in the long term for a therapeutic approach rather than to another".

Links: http://www.congressomedico.it/congressi/2006/ddw/23_mag_art_4.asppubblicato daA.Z. a01.40

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